GLP-1 DRUGS

NEWS: The Indian governmentàinspected businesses following the flooding of the market with generic GLP-1 drugs and a significant drop in their prices.

ABOUT

• Glucagon-like peptide-1 (GLP-1) àreceptor agonists : are a class of medications that mimic a natural hormone produced in the intestines.
• In Indiaà these medicines are strictly regulated+ can only be prescribed by endocrinologists, internal medicine specialists, and cardiologists.
• Developed Byà global pharmaceutical companies (such as Novo Nordisk and Eli Lilly) to manage chronic metabolic conditions.
• Generic versions produced by various manufacturers have flooded the marketà leading to increased accessibility and crashing prices.

Objective

• Primary objectiveà To treat Type 2 diabetes by stimulating insulin production.
• Also specifically approved for the medical management of obesity.

Key Characteristics

• Hormone MimicryàThey function by mimicking the GLP-1 hormoneàtargets areas of the brain that regulate appetite and food intake.
• Blood Sugar RegulationàThey stimulate the release of insulin from the pancreas in response to rising blood glucose levels.
• Digestion Satietyà Slow down gastric emptying, making the patient feel full for a longer duration.
• Diverse Formulationsà Available as both injectable+ oral medications depending on the specific generic or brand version.